Anthocyanin as neuroprotector for methamphetamine-induced neurotoxicity


  • Putu Asih Primatanti Udayana University, Denpasar, Indonesia
  • I Made Jawi Udayana University, Denpasar, Indonesia



anthocyanin, methamphetamine, neurotoxicity, neuroprotector


Methamphetamines are chemicals that might affect brain function and causes the development of addiction and other brain pathologies. It increased dopamine stimulation and would increase the formation of free radicals leading to dopaminergic neurotoxicity. Various therapeutic targets have been developed to prevent or minimize the negative effects of methamphetamine use. Increased level of oxidative stress has been considered as a potential trigger for neurotoxicity hence the expected ability for the administration of antioxidants to prevent damages caused by free radicals. The administration of antioxidants is expected to provide protective effects and prevent further damages created by methamphetamine exposure. Anthocyanin is a type of flavonoid is a potentially effective neuroprotector candidate for preventing neuronal cell death reduction, and this compound works with various mechanisms.


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How to Cite

Primatanti, P. A., & Jawi, I. M. (2019). Anthocyanin as neuroprotector for methamphetamine-induced neurotoxicity. International Journal of Health & Medical Sciences, 3(1), 11-16.



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