Correlation between magnetic resonance imaging (MRI) and dynamic mechanical analysis (DMA) in assessing consistency of brain tumor

Januardi Rifian Jani; Abdul Hafid Bajamal; Sri Andreani Utomo; Muhammad Arifin Parenrengi; Asra Al Fauzi; Budi Utomo; Yanurita Dwihapsari

doi:10.31295/ijhms.v4n2.1737

Authors

Januardi Rifian Jani Department of Neurosurgery, Faculty of Medicine of Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Abdul Hafid Bajamal
hfbajamal@gmail.com
Department of Neurosurgery, Faculty of Medicine of Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Sri Andreani Utomo Department of Radiology, Faculty of Medicine of Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Muhammad Arifin Parenrengi Department of Neurosurgery, Faculty of Medicine of Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Asra Al Fauzi Department of Neurosurgery, Faculty of Medicine of Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Budi Utomo Department of Public Health, Faculty of Medicine of Universitas Airlangga, Surabaya, Indonesia
Yanurita Dwihapsari Department of Physics, Faculty of Science of Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia

Keywords:

apparent diffusion coefficient (ADC), brain tumor, dynamic mechanical analysis (DMA), fractional anisotropy (FA), magnetic resonance imaging (MRI), modulus value, T2 weighted image (T2WI)

Abstract

Management of brain tumors require various disciplines collaboration. The choice of surgery equipment are based on accurate preoperative data of the brain tumor consistency. Non-invasive method of measuring brain tumor consistency can use MRI. Therefore, authors aim to analyze the correlation between MRI and DMA in assessing brain tumor consistency. This research is observational analytic study to find out the relationship between ADC ratio, T2-WI intensity, and FA value of brain tumor with its consistency using DMA modulus value after surgery. As comparison, we use agarose with four different concentrations. This study also looks for relationship between ADC value, FA value, and T2-WI intensity of agarose with its modulus value on DMA device. We followed the patients since they have diagnosed with brain tumor until post-surgery. The Spearman correlation test shows correlation coefficient and p-value between ADC ratio, FA value, T2WI intensity and modulus in brain tumor which are r=0.026(p=0.915), r=0.549(p=0.015), and r= -0.181(p=0.459) respectively, also between ADC, FA value, T2WI intensity and modulus in agarose are r=0.600(p=0.400), r= -0.800(p=0.200), and r=0.632(p=0.368) respectively. So, there is correlation between FA values and modulus in brain tumor. However, the result of other variables did not show any correlation from this study.

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