The relationship between saliva 17 beta-estradiol levels with anxiety and depression in menopause paramedic at Prof I.G.N.G Ngoerah Hospital Denpasar


  • Petrus Agustinus Seda Sega Udayana University, Denpasar, Bali, Indonesia
  • Anak Ayu Sri Wahyuni Udayana University, Denpasar, Bali, Indonesia | Prof. Dr. I.G.N.G. Ngoerah Hospital, Denpasar, Bali, Indonesia
  • Ni Ketut Sri Diniari Udayana University, Denpasar, Bali, Indonesia | Prof. Dr. I.G.N.G. Ngoerah Hospital, Denpasar, Bali, Indonesia
  • I Wayan Gede Artawan Eka Putra Udayana University, Denpasar, Bali, Indonesia


17β estradiol salivary levels, anxiety, depression, estradiol, estrogen, hospital anxiety and depression scale (HADS)


Background: Hospital Services rely on Medical and Paramedics at the Hospital, Hospital Paramedic services, especially women, are greatly influenced by mood, in women it is especially influenced by hormonal balance, including menstruation and menopause. The drop in estrogen levels after menopause causes many physical and emotional changes. Estradiol is the largest estrogen. It is estimated that the number of women who have menopause will experience a very significant increase of estradiol. Methods: An analytic observational study with a cross-sectional study design on 85 menopausal paramedics at Prof I.G.N.G Ngoerah Hospital Denpasar using a Hospital Anxiety and Depression Scale (HADS) questionnaire and examined salivary levels of 17? estradiol and looked for its relationship with anxiety and depression. Results: Based on the low salivary 17? estradiol level of the sample aged above 50 years (76.5%). Outpatient (75%), underweight (100%), married status (74.4%), and sample >5 years (76.5%). It is also a significant result where the salivary 17? estradiol level is lower in the sample compared to anxiety and depression complaints, with the chi-square test (p-value = <0.001). Conclusion: There is a significant relationship between low salivary 17? estradiol levels and complaints of anxiety and depression in menopausal paramedics.


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How to Cite

Sega, P. A. S., Wahyuni, A. A. S., Diniari, N. K. S., & Putra, I. W. G. A. E. (2023). The relationship between saliva 17 beta-estradiol levels with anxiety and depression in menopause paramedic at Prof I.G.N.G Ngoerah Hospital Denpasar. International Journal of Health & Medical Sciences, 6(3), 130-139.

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