Antenatal ultrasonographic detection of a rare intrauterine unilateral renal mass: A case of Congenital Wilms' Tumor

Niko Koridze; Mariam Morchadze; Tsotne Dadiani; Nino Kargadze; Mariam Sulava; Keti Kebadze; Melita Modebadze; Mariam Dvaladze; Ketevani Azikuri; Sofiko Gogshadze

doi:10.21744/ijhms.v8n2.2390

Antenatal ultrasonographic detection of a rare intrauterine unilateral renal mass

A case of Congenital Wilms' Tumor

https://doi.org/10.21744/ijhms.v8n2.2390

Authors

Niko Koridze Zhordania Medical Center, Tbilisi, Georgia
Mariam Morchadze Medical Expert in the Institution of Social Research Tbilisi, Georgia
Tsotne Dadiani Zhordania Medical Center, Tbilisi, Georgia
Nino Kargadze Zhordania Medical Center Neonatologist, Tbilisi, Georgia
Mariam Sulava Zhordania Medical Center Tbilisi, Georgia
Keti Kebadze Tbilisi State Medical University, Tbilisi, Georgia
Melita Modebadze Caucasus International University, Georgia
Mariam Dvaladze Tbilisi State Medical University, Tbilisi, Georgia
Ketevani Azikuri Tbilisi State Medical University, Tbilisi, Georgia
Sofiko Gogshadze Tbilisi State Medical University, Tbilisi, Georgia

Keywords:

congenital, infants, nephroblastoma, unilateral, Wilms tumor

Abstract

Congenital Wilms’ tumor is an exceptionally rare variant of nephroblastoma, diagnosed either in utero or within the first 30 days of life. Its clinical presentation and biological behavior may differ from the typical pediatric form, requiring a specialized approach to diagnosis and treatment. We present a case of a full-term newborn with a unilateral congenital Wilms’ tumor, initially detected during prenatal ultrasonography as an abdominal mass. Postnatal evaluations, including contrast-enhanced computed tomography (CT) and laboratory studies, confirmed the presence of a renal tumor confined to the left kidney. The patient underwent surgical resection via nephrectomy on day seven of life. Histopathological examination revealed Wilms’ tumor stage II based on surgical and pathological findings. Postoperative recovery was uneventful, and the patient was started on adjuvant chemotherapy according to pediatric oncology protocols. This case underscores the value of early prenatal detection, multidisciplinary management, and individualized therapeutic planning in achieving favorable outcomes for neonates with congenital Wilms’ tumor.

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References

Daniel, S. J. (2006). The upper airway: congenital malformations. Paediatric respiratory reviews, 7, S260-S263. https://doi.org/10.1016/j.prrv.2006.04.227

Fitria, F., Ahmad, M., Hatijar, H., Argaheni, N. B., & Susanti, N. Y. (2022). Monitoring combination of intermittent auscultation and palpation of contractions on oxygen saturation of newborns. International Journal of Health & Medical Sciences, 5(3), 221-227. https://doi.org/10.21744/ijhms.v5n3.1930

Govender, D. (2000). The pathology of nephroblastoma. Current Diagnostic Pathology, 6(1), 45-54. https://doi.org/10.1054/cdip.2000.0012

Martínez, C. H., Dave, S., & Izawa, J. (2010). Wilms’ tumor. Diseases of DNA Repair, 196-209.

Naggar, A., Assila, S., Laasri, K., Andour, H., Izi, Z., Lamalmi, N., ... & Chat, L. (2024). Bilateral Nephroblastomatosis With a Unilateral Wilms Tumor: A Case Report Highlighting Imaging Characteristics. Global Pediatric Health, 11, 2333794X231224566.

Neville, H. L., & Ritchey, M. L. (2000). WILMS'TUMOR: Overview of National Wilms' Tumor Study Group Results. Urologic Clinics of North America, 27(3), 435-442. https://doi.org/10.1016/S0094-0143(05)70091-4

Safaei, N., Kamran, H., Anbardar, M. H., Bordbar, M., Zekavat, O. R., & Forooghi, M. (2023). Large retroperitoneal teratoma presenting with unilateral hydronephrosis in an infant: a case report and review of the literature. Case Reports in Oncology, 16(1), 1041-1047.

Published

2025-05-23

How to Cite

Koridze, N., Morchadze, M., Dadiani, T., Kargadze, N., Sulava, M., Kebadze, K., Modebadze, M., Dvaladze, M., Azikuri, K., & Gogshadze, S. (2025). Antenatal ultrasonographic detection of a rare intrauterine unilateral renal mass: A case of Congenital Wilms’ Tumor. International Journal of Health & Medical Sciences, 8(2), 30-38. https://doi.org/10.21744/ijhms.v8n2.2390

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Issue

Vol. 8 No. 2 (2025): International Journal of Health & Medical Sciences

Section

Peer Review Articles

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